Remember the Reality show Rock Of Love (?), It was made pretty clear that Brett Michaels  prefers girls who are let's say very adventurous. "Talk Dirty To Me" was Poison's first hit and he sings about just this kind of girl in this song.

It's the girl that will make love just about anywhere, anytime and yes talk dirty.

Probably not the girl you'd bring home to meet the parents or maybe even marry  but always a good time, if you catch my drift.
The song is also featured on their album, 'Look What The Cat Dragged In' and on the  video game Guitar Hero III: Legends of Rock.
The song reached 40th on VH1'a all time hard rock songs of all time.
The song was a big hit for the band on the International level as well.